The Bayin Lab studies molecular mechanisms that regulate stem cell behaviours and age-dependent regenerative mechanisms in the brain.
A pseudocolored image of the neonatal mouse cerebellum shows the laminar structure of the neonatal cerebellum and the nestin-expressing progenitors and astroglia.
We study the mouse cerebellum as a paradigm to identify cell-intrinsic and -extrinsic mechanisms regulating key stem cell behaviors during development, and molecular factors that inhibit effective regeneration in the adult brain or support regeneration in newborns.
Our ultimate goal is to discover how the regenerative potential of the endogenous neural stem cells can be harnessed in human disease.